What molecule do commensal streptococci produce during the conversion of pyruvate to acetyl phosphate?

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Prepare for the Microbiology and Immunology 6400 Oral Intermicrobial Interactions Test. Study with engaging materials, flashcards, and multiple-choice questions. Each question offers hints and detailed explanations. Ace your exam today!

Multiple Choice

What molecule do commensal streptococci produce during the conversion of pyruvate to acetyl phosphate?

Explanation:
Hydrogen peroxide is produced. In commensal streptococci, the enzyme pyruvate oxidase uses pyruvate, inorganic phosphate, and oxygen to convert pyruvate into acetyl phosphate, releasing carbon dioxide and hydrogen peroxide in the process. This H2O2 acts as an antimicrobial by inhibiting neighboring bacteria in the oral biofilm, helping these streptococci compete. Lactic acid comes from a different pathway (pyruvate to lactate), water is not the specific byproduct of this step, and acetate would be formed later when acetyl phosphate is further processed, not during the initial conversion.

Hydrogen peroxide is produced. In commensal streptococci, the enzyme pyruvate oxidase uses pyruvate, inorganic phosphate, and oxygen to convert pyruvate into acetyl phosphate, releasing carbon dioxide and hydrogen peroxide in the process. This H2O2 acts as an antimicrobial by inhibiting neighboring bacteria in the oral biofilm, helping these streptococci compete. Lactic acid comes from a different pathway (pyruvate to lactate), water is not the specific byproduct of this step, and acetate would be formed later when acetyl phosphate is further processed, not during the initial conversion.

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